| 产品名称 | KRT10 antibody | anti KRT10 antibody | Biorbyt |
| 产品货号 | orb534714 |
| 产品价格 | 现货询价，电话：010-67529703 |
| 产品规格 | |
| 产品品牌 | Biorbyt |
| 产品概述 | |
| 产品详情 | |
| Product Name | KRT10 antibody |
|---|---|
| Catalog Number | orb534714 |
| Species/Host | Mouse |
| Reactivity | Animal, Canine, Human |
| Conjugation | Unconjugated |
| Tested applications | IHC-P |
| Immunogen | Recombinant full-lenth human KRT10 protein. |
| Target | This MAb recognizes a protein of 56.5kDa, identified as cytokeratin 10 (CK10). CK10 is expressed in all suprabasal layers of the epidermis. In the epidermis, expression of CK10 strictly parallels the extent of differentiation; it is absent in the basal layer, appears in the first suprabasal layers and increases in concentration towards the granular layer. However, CK10 is rarely detected in early stages of vulvar squamous carcinomas (tumors less than 2 cm, clinical stage I) regardless of the tumor grade. In larger and more advanced tumors (greater than 2 cm, clinical stages II and III), CK10 is detected very frequently. Expression of CK10 is related to maturation of malignant keratinocytes, being preferentially detected in more-differentiated parts. |
| Form/Appearance | 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml. |
| Storage | Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. |
| Note | For research use only. |
| Isotype | IgG1, kappa |
| Clonality | Monoclonal |
| Purity | Purified Ab with BSA and Azide at 200ug/ml |
| MW | 56.5 kDa |
| Clone ID | rKRT10/1275 |
| Uniprot ID | P13645 |
| Entrez | 3858 |
| Dilution Range | IHC-P: 0.1-0.2 μg/ml for 30 min at RT |
| 产品资料 |