产品名称 | Acetylshikonin | Biorbyt |
产品货号 | orb390014 |
产品价格 | 现货询价,电话:010-67529703 |
产品规格 | |
产品品牌 | Biorbyt |
产品概述 | |
产品详情 | |
Product Name | Acetylshikonin |
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Catalog Number | orb390014 |
Conjugation | Unconjugated |
Hazard Information | Non-Toxic |
Target | Acetylshikonin |
Form/Appearance | Powder |
Storage | Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months at 2-8°C. |
Note | For research use only. |
Purity | >98% |
Formula | C18H18O6 |
MW | 330.33 |
CAS Number | [54984-93-9] |
Source | The roots of Lithosperraum erythrorhizon Sieb. et Zucc. |
Activity | 1. Acetylshikonin (ASK), a derivate of shikonin, can effectively inhibit tumor cells. 2. Acetylshikonin can be used to treat hepatocellular carcinoma cells expressing hepatitis B virus X protein (HBX) by inducing ER stress , an oncoprotein from hepatitis B virus. 3. Acetylshikonin exhibits the most potent antiapoptosis activity through the inhibition of the generation of reactive oxygen species as well as protection of the loss of mitochondria membrane potential. 4. Acetylshikonin inhibits the production of eicosanoid, is due to the attenuation of cytosolic phospholipase A(2) membrane recruitment via the decrease in [Ca(2+)](i) and to the blockade of cyclooxygenase and 5-lipoxygenase activity. |
Application Notes | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
产品资料 |