| 产品名称 |
GZMB antibody | anti GZMB antibody | Biorbyt |
| 产品货号 |
orb534660 |
| 产品价格 |
现货询价，电话：010-67529703
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| 产品规格 |
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| 产品品牌 |
Biorbyt |
| 产品概述 |
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| 产品详情 |
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| Product Name | GZMB antibody |
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| Catalog Number | orb534660 |
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| Species/Host | Rabbit |
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| Reactivity | Human |
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| Conjugation | Unconjugated |
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| Tested applications | FACS, IF, IHC-P, WB |
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| Immunogen | Recombinant fragment (115 Amino acid residues; aa 73-187) of human Granzyme B protein |
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| Target | Granzyme B is a member of the granule serine protease family stored specifically in NK cells or cytotoxic T cells. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'non-self' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. Granzyme B is crucial for the rapid induction of target cell apoptosis by CTLs in the cell-mediated immune response. Granzyme B is useful as a marker in the identification of NK/T-cell lymphomas. High percentages of cytotoxic T-cells have been shown to be an unfavorable prognostic indicator in HodgkinÄ€™s Disease. |
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| Form/Appearance | 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA at 1.0mg/ml. |
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| Storage | Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. |
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| Note | For research use only. |
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| Isotype | IgG |
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| Clonality | Polyclonal |
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| Purity | Purified Ab with BSA and Azide at 200ug/ml |
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| MW | 29-32 kDa |
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| Uniprot ID | P10144 |
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| Entrez | 3002 |
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| Dilution Range | FACS: 0.5-1 μg/million cells in 0.1ml , IF: 0.5-1 μg/ml , WB: 1-2 μg/ml , IHC-P: 0.5-1 μg/ml for 30 minutes at RT |
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| 产品资料 |
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