| 产品名称 |
ZAP70 antibody | anti ZAP70 antibody | Biorbyt |
| 产品货号 |
orb534955 |
| 产品价格 |
现货询价，电话：010-67529703
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| 产品规格 |
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| 产品品牌 |
Biorbyt |
| 产品概述 |
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| 产品详情 |
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| Product Name | ZAP70 antibody |
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| Catalog Number | orb534955 |
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| Species/Host | Mouse |
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| Reactivity | Human |
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| Conjugation | Unconjugated |
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| Tested applications | ELISA, IHC-P |
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| Immunogen | Recombinant fragment (around aa 247-382) of human ZAP70 protein (exact sequence is proprietary) |
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| Target | ZAP70 is a 70kDa protein tyrosine kinase found in T-cells and natural killer cells. Control of this protein translation is via the IgVH gene. ZAP70 protein is expressed in leukemic cells of approximately 25% of chronic lymphocytic leukemia (CLL) cases as well. Anti-ZAP70 expression is an excellent surrogate marker for the distinction between the Ig-mutated (anti-ZAP70 negative) and Ig-unmutated (anti-ZAP70 positive) CLL subtypes and can identify patient groups with divergent clinical courses. The anti-ZAP70 positive Ig-unmutated CLL cases have been shown to have a poorer prognosis. |
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| Form/Appearance | 1mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml. |
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| Storage | Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. |
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| Note | For research use only. |
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| Isotype | IgG1, kappa |
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| Clonality | Monoclonal |
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| Purity | Purified Ab with BSA and Azide at 200ug/ml |
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| MW | 70 kDa |
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| Clone ID | ZAP70/2047 |
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| Uniprot ID | P43403 |
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| Entrez | 7535 |
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| Dilution Range | ELISA: 2-4 μg/ml, IHC-P: 1-2 μg/ml for 30 minutes at RT |
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| 产品资料 |
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