产品名称 |
CD3E antibody | anti CD3E antibody | Biorbyt |
产品货号 |
orb534983 |
产品价格 |
现货询价,电话:010-67529703
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产品规格 |
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产品品牌 |
Biorbyt |
产品概述 |
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产品详情 |
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Product Name | CD3E antibody |
Catalog Number | orb534983 |
Species/Host | Mouse |
Reactivity | Human |
Conjugation | Unconjugated |
Tested applications | ELISA, FACS, IHC-P |
Immunogen | Human infant thymocytes and peripheral blood lymphocytes from a Sezary Syndrome donor |
Target | Recognizes the -chain of CD3, which consists of five different polypeptide chains (designated as gamma, delta, epsilon, zeta, and eta) with MW ranging from 16-28kDa. The CD3 complex is closely associated at the lymphocyte cell surface with the T cell antigen receptor (TCR). Reportedly, CD3 complex is involved in signal transduction to the T cell interior following antigen recognition. The CD3 antigen is first detectable in early thymocytes and probably represents one of the earliest signs of commitment to the T cell lineage. In cortical thymocytes, CD3 is predominantly intra-cytoplasmic. However, in medullary thymocytes, it appears on the T cell surface. CD3 antigen is a highly specific marker for T cells, and is present in majority of T cell neoplasms. |
Form/Appearance | 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml. |
Storage | Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. |
Note | For research use only. |
Isotype | IgG1, kappa |
Clonality | Monoclonal |
Purity | Purified Ab with BSA and Azide at 200ug/ml |
MW | 20 kDa |
Clone ID | UCHT1 |
Uniprot ID | P07766 |
Entrez | 916 |
Dilution Range | ELISA: 2-4 μg/ml, FACS: 0.5-1 μg/million cells, IHC-P: 1-2 μg/ml for 30 minutes at RT |
产品资料 |
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