产品名称 CD22 antibody | anti CD22 antibody | Biorbyt
产品货号 orb535002
产品价格 现货询价,电话:010-67529703
产品规格
产品品牌 Biorbyt
产品概述
产品详情
Product Name CD22 antibody
Catalog Number orb535002
Species/HostMouse
ReactivityHuman
ConjugationUnconjugated
Tested applicationsELISA, IHC-P
Immunogen Recombinant fragment of human CD22 protein (around aa 52-178) (exact sequence is proprietary)
Target Recognizes a protein of 130-140kDa, identified as CD22 (also known as BL-CAM). CD22 expression is restricted to normal and neoplastic B cells and is absent from other haemopoietic cell types. In B-cell ontogeny, CD22 is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface as B cells mature to become IgD+. It is not expressed by plasma cells, CD22 is found highly expressed in follicular mantle and marginal zone B-cells, and while germinal center B-cells are relatively weak. CD22 is a member of the immunoglobulin superfamily and serves as an adhesion receptor for sialic acid-bearing ligands expressed on erythrocytes and all leukocyte classes. It also associates with tyrosine kinases and play a role in signal transduction and B-cell activation.
Form/Appearance 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Storage Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months.
Note For research use only.
Isotype IgG2b, kappa
ClonalityMonoclonal
Purity Purified Ab with BSA and Azide at 200ug/ml
MW 130-140 kDa
Clone ID BLCAM/1796
Uniprot ID P20273
Entrez 933
Dilution Range ELISA: 2-4 μg/ml, IHC-P: 1-2 μg/ml for 30 minutes at RT
产品资料