产品名称 |
CD22 antibody | anti CD22 antibody | Biorbyt |
产品货号 |
orb535002 |
产品价格 |
现货询价,电话:010-67529703
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产品规格 |
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产品品牌 |
Biorbyt |
产品概述 |
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产品详情 |
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Product Name | CD22 antibody |
Catalog Number | orb535002 |
Species/Host | Mouse |
Reactivity | Human |
Conjugation | Unconjugated |
Tested applications | ELISA, IHC-P |
Immunogen | Recombinant fragment of human CD22 protein (around aa 52-178) (exact sequence is proprietary) |
Target | Recognizes a protein of 130-140kDa, identified as CD22 (also known as BL-CAM). CD22 expression is restricted to normal and neoplastic B cells and is absent from other haemopoietic cell types. In B-cell ontogeny, CD22 is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface as B cells mature to become IgD+. It is not expressed by plasma cells, CD22 is found highly expressed in follicular mantle and marginal zone B-cells, and while germinal center B-cells are relatively weak. CD22 is a member of the immunoglobulin superfamily and serves as an adhesion receptor for sialic acid-bearing ligands expressed on erythrocytes and all leukocyte classes. It also associates with tyrosine kinases and play a role in signal transduction and B-cell activation. |
Form/Appearance | 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml. |
Storage | Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. |
Note | For research use only. |
Isotype | IgG2b, kappa |
Clonality | Monoclonal |
Purity | Purified Ab with BSA and Azide at 200ug/ml |
MW | 130-140 kDa |
Clone ID | BLCAM/1796 |
Uniprot ID | P20273 |
Entrez | 933 |
Dilution Range | ELISA: 2-4 μg/ml, IHC-P: 1-2 μg/ml for 30 minutes at RT |
产品资料 |
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