产品名称 |
HLA-DP antibody | anti HLA-DP antibody | Biorbyt |
产品货号 |
orb534667 |
产品价格 |
现货询价,电话:010-67529703
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产品规格 |
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产品品牌 |
Biorbyt |
产品概述 |
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产品详情 |
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Product Name | HLA-DP antibody |
Catalog Number | orb534667 |
Species/Host | Rabbit |
Reactivity | Human |
Conjugation | Unconjugated |
Tested applications | ELISA, IHC-P |
Immunogen | Non-T, non-B human acute lymphoblastic leukemia REH6 cell line |
Target | Reacts with a common epitope of human major histocompatibility (MHC) class II antigens, HLA-DP, -DQ and -DR. Human MHC class II antigens are transmembrane glycoproteins composed of an ï ¡ chain (36kDa) and a ï ¢ chain (27kDa). They are expressed primarily on antigen presenting cells such as B lymphocytes, monocytes, macrophages, and thymic epithelial cells and are also present on activated T lymphocytes. Human MHC class II genes are located in the HLA-D region that encodes at least six ï ¡ and ten ï ¢ chain genes. Three loci, DR, DQ and DP, encode the major expressed products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells. They, therefore, have a critical role in the initiation of the immune response. It has been shown that some autoimmune diseases are associated with certain class II alleles. |
Form/Appearance | 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml. |
Storage | Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. |
Note | For research use only. |
Isotype | IgG |
Clonality | Monoclonal |
Purity | Purified Ab with BSA and Azide at 200ug/ml |
MW | 33-35 kDa |
Clone ID | HLA-DPB1/2967R |
Uniprot ID | P04440 |
Entrez | 3115 |
Dilution Range | ELISA: 1-5 μg/ml, IHC-P: 0.5-1 μg/ml for 30 minutes at RT |
产品资料 |
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