产品名称 HLA-DP antibody | anti HLA-DP antibody | Biorbyt
产品货号 orb534667
产品价格 现货询价,电话:010-67529703
产品规格
产品品牌 Biorbyt
产品概述
产品详情
Product Name HLA-DP antibody
Catalog Number orb534667
Species/HostRabbit
ReactivityHuman
ConjugationUnconjugated
Tested applicationsELISA, IHC-P
Immunogen Non-T, non-B human acute lymphoblastic leukemia REH6 cell line
Target Reacts with a common epitope of human major histocompatibility (MHC) class II antigens, HLA-DP, -DQ and -DR. Human MHC class II antigens are transmembrane glycoproteins composed of an ï  ¡ chain (36kDa) and a ï  ¢ chain (27kDa). They are expressed primarily on antigen presenting cells such as B lymphocytes, monocytes, macrophages, and thymic epithelial cells and are also present on activated T lymphocytes. Human MHC class II genes are located in the HLA-D region that encodes at least six ï  ¡ and ten ï  ¢ chain genes. Three loci, DR, DQ and DP, encode the major expressed products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells. They, therefore, have a critical role in the initiation of the immune response. It has been shown that some autoimmune diseases are associated with certain class II alleles.
Form/Appearance 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Storage Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months.
Note For research use only.
Isotype IgG
ClonalityMonoclonal
Purity Purified Ab with BSA and Azide at 200ug/ml
MW 33-35 kDa
Clone ID HLA-DPB1/2967R
Uniprot ID P04440
Entrez 3115
Dilution Range ELISA: 1-5 μg/ml, IHC-P: 0.5-1 μg/ml for 30 minutes at RT
产品资料