产品名称 SPTBN2 antibody | anti SPTBN2 antibody | Biorbyt
产品货号 orb534895
产品价格 现货询价,电话:010-67529703
产品规格
产品品牌 Biorbyt
产品概述
产品详情
Product Name SPTBN2 antibody
Catalog Number orb534895
Species/HostRabbit
ReactivityHuman
ConjugationUnconjugated
Tested applicationsELISA, IHC-P, WB
Immunogen Recombinant human SPTBN2 fragment (aa356-475) (exact sequence is proprietary)
Target Spectrin is an actin binding protein that is a major component of the plasma membrane skeleton. Spectrins function as membrane organizers and stabilizers by forming dimers, tetramers and higher polymers. Vertebrate spectrins have two alpha-subunits (alpha-I/alpha-II), four beta-subunits (beta-I-beta-IV) and a beta-H subunit creating diversity and specialization of function. Spectrin α and spectrin β are present in erythrocytes, whereas spectrin α II (also designated fodrin α) and spectrin β I (also designated fodrin β) are present in other somatic cells. The spectrin tetramers in erythrocytes act as barriers to lateral diffusion, but spectrin dimers seem to lack this function. Spectrin β III is highly homologous to both spectrin β I and spectrin β II. Spectrin β III is highly expressed in brain, kidney, pancreas and liver, and at lower levels in lung and placenta. Spectrin beta 3 is primarily expressed in nervous tissues with highest expression levels in the cerebellum, where it is found in Purkinje cell soma and dendrites.
Form/Appearance 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Storage Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months.
Note For research use only.
Isotype IgG
ClonalityMonoclonal
Purity Purified Ab with BSA and Azide at 200ug/ml
MW 246 kDa
Clone ID SPTBN2/2894R
Uniprot ID O15020
Entrez 6712
Dilution Range ELISA: 2-4 μg/ml, WB: 0.5-1.0 μg/ml, IHC-P: 0.5-1.0 μg/ml for 30 minutes at RT
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