产品名称 |
SPTBN2 antibody | anti SPTBN2 antibody | Biorbyt |
产品货号 |
orb534895 |
产品价格 |
现货询价,电话:010-67529703
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产品规格 |
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产品品牌 |
Biorbyt |
产品概述 |
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产品详情 |
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Product Name | SPTBN2 antibody |
Catalog Number | orb534895 |
Species/Host | Rabbit |
Reactivity | Human |
Conjugation | Unconjugated |
Tested applications | ELISA, IHC-P, WB |
Immunogen | Recombinant human SPTBN2 fragment (aa356-475) (exact sequence is proprietary) |
Target | Spectrin is an actin binding protein that is a major component of the plasma membrane skeleton. Spectrins function as membrane organizers and stabilizers by forming dimers, tetramers and higher polymers. Vertebrate spectrins have two alpha-subunits (alpha-I/alpha-II), four beta-subunits (beta-I-beta-IV) and a beta-H subunit creating diversity and specialization of function. Spectrin α and spectrin β are present in erythrocytes, whereas spectrin α II (also designated fodrin α) and spectrin β I (also designated fodrin β) are present in other somatic cells. The spectrin tetramers in erythrocytes act as barriers to lateral diffusion, but spectrin dimers seem to lack this function. Spectrin β III is highly homologous to both spectrin β I and spectrin β II. Spectrin β III is highly expressed in brain, kidney, pancreas and liver, and at lower levels in lung and placenta. Spectrin beta 3 is primarily expressed in nervous tissues with highest expression levels in the cerebellum, where it is found in Purkinje cell soma and dendrites. |
Form/Appearance | 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml. |
Storage | Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. |
Note | For research use only. |
Isotype | IgG |
Clonality | Monoclonal |
Purity | Purified Ab with BSA and Azide at 200ug/ml |
MW | 246 kDa |
Clone ID | SPTBN2/2894R |
Uniprot ID | O15020 |
Entrez | 6712 |
Dilution Range | ELISA: 2-4 μg/ml, WB: 0.5-1.0 μg/ml, IHC-P: 0.5-1.0 μg/ml for 30 minutes at RT |
产品资料 |
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