产品名称 |
TYRP1 antibody | anti TYRP1 antibody | Biorbyt |
产品货号 |
orb534939 |
产品价格 |
现货询价,电话:010-67529703
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产品规格 |
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产品品牌 |
Biorbyt |
产品概述 |
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产品详情 |
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Product Name | TYRP1 antibody |
Catalog Number | orb534939 |
Species/Host | Rabbit |
Reactivity | Human |
Conjugation | Unconjugated |
Tested applications | ELISA, IHC-P |
Immunogen | Recombinant fragment of human TYRP1 protein (around aa 257-377) (exact sequence is proprietary) |
Target | It reacts with a 75kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi. Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death. |
Form/Appearance | 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml. |
Storage | Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. |
Note | For research use only. |
Isotype | IgG |
Clonality | Monoclonal |
Purity | Purified Ab with BSA and Azide at 200ug/ml |
MW | 75 kDa |
Clone ID | TYRP1/2340R |
Uniprot ID | P17643 |
Entrez | 7306 |
Dilution Range | ELISA: 2-4 μg/ml, IHC-P: 1-2 μg/ml for 30 minutes at RT |
产品资料 |
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