| 产品名称 |
VTCN1 antibody | anti VTCN1 antibody | Biorbyt |
| 产品货号 |
orb534961 |
| 产品价格 |
现货询价，电话：010-67529703
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| 产品规格 |
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| 产品品牌 |
Biorbyt |
| 产品概述 |
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| 产品详情 |
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| Product Name | VTCN1 antibody |
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| Catalog Number | orb534961 |
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| Species/Host | Rabbit |
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| Reactivity | Human |
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| Conjugation | Unconjugated |
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| Tested applications | ELISA, IHC-P |
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| Immunogen | Recombinant human B7-H4 protein fragment (exact sequence is proprietary) |
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| Target | T cell activation and immune function are regulated by the innate immune system through positive and negative costimulatory proteins. One such protein, B7-H4 (B7-homolog 4), belongs to the B7 immunoglobulin superfamily of ligand-lymphocyte interacting proteins. Expressed primarily on the membrane of lymphoid cells, B7-H4 is an immuno-inhibitory protein that interacts with receptors on the surface of T lymphocytes, thus mediating cellular and humoral immune responses. Overexpression of the B7-H4 protein is associated with certain malignancies, including ovarian and breast cancer, as its interaction with T cells suppresses tumor-associated immunity. Current research suggests that, similar to Mucin 16 (CA-125), B7-H4 may be a useful biomarker for the early detection of ovarian cancer. |
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| Form/Appearance | 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml. |
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| Storage | Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. |
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| Note | For research use only. |
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| Isotype | IgG |
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| Clonality | Monoclonal |
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| Purity | Purified Ab with BSA and Azide at 200ug/ml |
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| MW | 35 kDa |
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| Clone ID | B7H4/2652R |
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| Uniprot ID | Q7Z7D3 |
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| Entrez | 79679 |
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| Dilution Range | ELISA: 2-4 μg/ml, IHC-P: 1-2 μg/ml for 30 minutes at RT |
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| 产品资料 |
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