| 产品名称 |
c-Myc antibody (Biotin) | anti c-Myc antibody (Biotin) | Biorbyt |
| 产品货号 |
orb222741 |
| 产品价格 |
现货询价，电话：010-67529703
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| 产品规格 |
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| 产品品牌 |
Biorbyt |
| 产品概述 |
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| 产品详情 |
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| Product Name |
c-Myc antibody (Biotin) |
| Catalog Number |
orb222741 |
| Species/Host |
Mouse |
| Reactivity |
Human |
| Conjugation |
Biotin |
| Tested applications |
FACS, IHC-P, IP, WB |
| Immunogen |
Synthetic peptide sequence (AEEQKLISEEDLL) corresponding to the C-terminal region of human c-Myc. |
| Target |
c-Myc (Biotin). The antibody 9E10 may be used to detect the c-Myc tag. The c-myc gene (8q24 on human chromosome) is the cellular homologue of the v-myc gene originally isolated from an avian myelocytomatosis virus. The c-Myc protein is a transcription factor (nuclear localization). c-Myc is commonly activated in a variety of tumor cells and plays an important role in cellular proliferation, differentiation, apoptosis and cell cycle progression. The phosphorylation of c-Myc has been investigated and previous studies have suggested a functional association between phosphorylation at Thr58/Ser62 by glycogen synthase kinase 3, cyclin-dependent kinase, ERK2 and C-Jun N-terminal Kinase (JNK) in cell proliferation and cell cycle regulation. In normal cells the expression of c-Myc is tightly regulated but in human cancers c-Myc is frequently deregulated. c-Myc is also essential for tumor cell development in vasculogenesis and angiogenesis that distribute blood throughout the cells. |
| Alternative Names |
(click to expand)
Cellular myelocytomatosis oncogene
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| Form/Appearance |
PBS with 15 mM sodium azide, approx. pH 7.4 |
| Storage |
Store at 2-8°C. |
| Note |
For research use only. |
| Isotype |
IgG1 |
| Clonality |
Monoclonal |
| Clone ID |
90000000000 |
| 产品资料 |
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