| 产品名称 | HLA-DQ antibody | anti HLA-DQ antibody | Biorbyt |
| 产品货号 | orb534668 |
| 产品价格 | 现货询价，电话：010-67529703 |
| 产品规格 | |
| 产品品牌 | Biorbyt |
| 产品概述 | |
| 产品详情 | |
| Product Name | HLA-DQ antibody |
|---|---|
| Catalog Number | orb534668 |
| Species/Host | Rabbit |
| Reactivity | Human, Porcine |
| Conjugation | Unconjugated |
| Tested applications | FACS, IHC-P |
| Immunogen | Recombinant full-length human HLA-DQ protein |
| Target | Recognizes a DQ antigen, which is a dimer of 60kDa. The class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B Lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35kDa. It is encoded by 5 exons; exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. with in the DQ molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to four different molecules. Typing for these polymorphisms is routinely done for bone marrow transplantation. This MAb strongly blocks cytotoxicity activity of T4-positive cytotoxic T cell clones. |
| Form/Appearance | 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml. |
| Storage | Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. |
| Note | For research use only. |
| Isotype | IgG2a, kappa |
| Clonality | Monoclonal |
| Purity | Purified Ab with BSA and Azide at 200ug/ml |
| MW | 60 kDa |
| Clone ID | HLA-DQA1/2866R |
| Uniprot ID | P01908 |
| Entrez | 3117 |
| Dilution Range | FACS: 1-2 μg/million cells , IHC-P: 0.5-1 μg/ml for 30 minutes at RT |
| 产品资料 |