| 产品名称 | ALPL antibody | anti ALPL antibody | Biorbyt |
| 产品货号 | orb534627 |
| 产品价格 | 现货询价，电话：010-67529703 |
| 产品规格 | |
| 产品品牌 | Biorbyt |
| 产品概述 | |
| 产品详情 | |
| Product Name | ALPL antibody |
|---|---|
| Catalog Number | orb534627 |
| Species/Host | Mouse |
| Reactivity | Bovine, Human |
| Conjugation | Unconjugated |
| Tested applications | FACS, IF, IHC-P |
| Immunogen | Bovine intestinal alkaline phosphatase |
| Target | There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. The exact physiological function of the alkaline phosphatases is not known. A proposed function of this form of the enzyme is matrix mineralization; however, mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to hypo-phosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects. The character of this disorder can vary, however, depending on the specific mutation since this determines age of onset and severity of symptoms. Alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. |
| Form/Appearance | 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml. |
| Storage | Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. |
| Note | For research use only. |
| Isotype | IgG1, kappa |
| Clonality | Monoclonal |
| Purity | Purified Ab with BSA and Azide at 200ug/ml |
| MW | 55 kDa |
| Clone ID | V17.1 |
| Uniprot ID | P05186 |
| Entrez | 249 |
| Dilution Range | FACS: 0.5-1 μg/million cells , IF: 0.5-1 μg/ml , IHC-P: 0.5-1 μg/ml for 30 minutes at RT |
| 产品资料 |