| 产品名称 | Calycosin | Biorbyt |
| 产品货号 | orb389993 |
| 产品价格 | 现货询价，电话：010-67529703 |
| 产品规格 | |
| 产品品牌 | Biorbyt |
| 产品概述 | |
| 产品详情 | |
| Product Name | Calycosin |
|---|---|
| Catalog Number | orb389993 |
| Conjugation | Unconjugated |
| Hazard Information | Non-Toxic |
| Target | Calycosin |
| Form/Appearance | Yellow powder |
| Storage | Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months at 2-8°C. |
| Note | For research use only. |
| Purity | >98% |
| Formula | C16H12O5 |
| MW | 284.26 |
| CAS Number | [20575-57-9] |
| Source | The herb of Astragalus membranaceus Bge. var. mongholicus |
| Activity | 1. Calycosin acts as a selective estrogen receptor modulator. 2. Calycosin induces apoptosis in human ovarian cancer SKOV3 cells by activating caspases and Bcl-2 family proteins. 3. Calycosin suppresses breast cancer cell growth via ERbeta-dependent regulation of IGF-1R, p38 MAPK and PI3K/Akt pathways. 4. Calycosin has antineoplastic effects against osteosarcoma through inducing apoptosis showing in vitro and in vivo investigations. 5. Calycosin was shown to induce angiogenesis in human umbilical vein endothelial cell cultures (HUVEC) in vitro. 6. Calycosin may be an effective skin-lightening agent that regulates the expression of melanogenic enzymes. Calycosin exhibited tyrosinase inhibitory activity with an IC(50) value of 38.4 microM. |
| Application Notes | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| 产品资料 |