产品名称 PGP9.5 antibody | anti PGP9.5 antibody | Biorbyt
产品货号 orb33715
产品价格 现货询价,电话:010-67529703
产品规格
产品品牌 Biorbyt
产品概述
产品详情
Product Name PGP9.5 antibody
Catalog Number orb33715
Species/HostRabbit
ReactivityHuman, Mouse, Rat
Predicted Reactivity Bovine, Monkey, Porcine, Equine
ConjugationUnconjugated
Tested applicationsELISA, FACS, ICC, IF, IHC-P, WB
Immunogen

This UCHL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 187-216 amino acids from the C-terminal region of human UCHL1.

Target PGP9.5
Alternative Names
Form/Appearance PBS with 0.09% (W/V) sodium azide
Storage Store at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Note For research use only.
Isotype IgG
ClonalityPolyclonal
Purity

Affinity purified

MW 24.824 kDa
Uniprot ID

P09936 (Human)

NCBI NP_004172.2
Entrez 7345
Dilution Range WB: 1:1000, IHC-P: 1:50-100, FACS: 1:10-50, IF/ICC: 1:10-50
Application Notes
Protein Information
Name UCHL1
Function Ubiquitin-protein hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. Also binds to free monoubiquitin and may prevent its degradation in lysosomes. The homodimer may have ATP-independent ubiquitin ligase activity.
Cellular Location Cytoplasm. Endoplasmic reticulum membrane; Lipid-anchor. Note=About 30% of total UCHL1 is associated with membranes in brain
Tissue Location Found in neuronal cell bodies and processes throughout the neocortex (at protein level). Expressed in neurons and cells of the diffuse neuroendocrine system and their tumors Weakly expressed in ovary. Down-regulated in brains from Parkinson disease and Alzheimer disease patients
产品资料