产品名称 MUC1 antibody | anti MUC1 antibody | Biorbyt
产品货号 orb137264
产品价格 现货询价,电话:010-67529703
产品规格
产品品牌 Biorbyt
产品概述
产品详情
Product Name MUC1 antibody
Catalog Number orb137264
Species/HostMouse
ReactivityHuman
ConjugationUnconjugated
Tested applicationsELISA, IHC-Fr, IHC-P
Immunogen MUC1 antibody was raised against high molecular weight (>300kD) glycoprotein from human milk-fat globule molecule.
Target MUC1. Binds with high efficiency to an epitope within the VNTR recombinant repeat peptide region of MUC1 molecule. Reacts with VNTR20 recombinant unglycosylated fragment of MUC1 protein (but not with monomeric MUC1 peptide), with deglycosylated and underglycosylated natural MUC1, but not with completely glycosylated MUC1. Belongs to MAb clusters 6 and 7 according to ISOMB TD-4 classification. Non cross-reactive with normal serum proteins and human tissues of nonepithelial origin.
Alternative Names
Form/Appearance PBS, pH 7.4, 0.1% sodium azide.
Concentration 8.2 mg/ml
Storage Store at -20°C; for Long term Store at +4°C. for Short term Avoid repeat freeze-thaw cycles.
Note For research use only.
Isotype IgG
ClonalityMonoclonal
Purity Protein A purified
Uniprot ID P15941
NCBI NM_002456; NP_002447.4
Dilution Range IHC-P:10 μg/ml
Application Notes Immunohistochemical and immunofluorescent detection of neoplastic breast epithelium. Works on frozen tissue sections. Construction of immunometric assay for MUC determination. ELISA tests for measurement of unglycosylated and underglycosylated tumor-associated MUC1mucins in human serum. Detection of unglycosylated MUC1. Can be used for immunohistochemical staining of paraffin and frozen sections of breast, lung and ovarian tumor tissues. Staining of paraffin-embedded tissue sections fixed in neutral-buffered formalin.
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