Under normal expression conditions, procalcitonin is immediately separated into three specific fragments: an N terminal residue, calcitonin and katacalcin. Levels of unprocessed Procalcitonin rise significantly after bacterial infection, trauma or shock. Recombinant Human Procalcitonin produced in E.coli is a single, non-glycosylated, polypeptide chain made up of 116 amino acids with a molecular weight of 12.8 kDa.