产品名称 | Recombinant Human Interferon–Inducible T Cell Alpha Chemoattractant, rHu I-TAC |
产品货号 | AK9702 |
产品价格 | 现货询价,电话:010-67529703 |
产品规格 | Choose an option1 mg100 µg20 µg5 µgClear |
产品品牌 | akronbiotech |
产品概述 | |
产品详情 |
![]() Interferon Inducible T-cell A Chemoattractant (I-TAC), or CXCL11, expressed at high levels in leukocytes, pancreas and liver exposed to IFNa, ß, and gamma.
For more information and to purchase products, please login. I-TAC is a potent chemoattractant for T cells activated by IL2. It has been reported that it also functions as a natural antagonist for CCR5. I-TAC is one of three chemokines known to bind the receptor CXCR3 (the two others being CXCL9 and CXCL10 (IP-10)) to act as a chemoattractant for IL-2 activated T cells. CXCL11 differs from the other CXCR3 ligands in that it has a higher receptor affinity, thus acts as a stronger agonist. Recombinant human I-TAC expressed in E. coli is a non- glycosylated protein, containing 73 amino acids and having a molecular mass of 8.3 kDa. |
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