Fibroblast growth factors are growth factors that play crucial roles in angiogenesis, embryonic development, and wound-healing. FGFs are also involved in the proliferation and differentiation of various cells and tissues. FGF is used to promote stem cells and cell lines in culture. rHu bFGF-147 (FGF-2) produced in E. coli is a single, non-glycosylated, polypeptide chain that contains 147 amino acids and has a molecular mass of 16.54 kDa.