Fibronectin is responsible for cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis.

Applications:

• Promote cell-substrate attachment
• Improve cellular differentiation
• Reduce variation in plating efficiency found in different serum batches

Plasma-Derived Fibronectin

Plasma fibronectin (pFN) is secreted by hepatocytes as a major protein component of blood. pFN opsonizes bacteria and helps form clots. Plasma FN is widely used in cell culture to help cells attach to the substrate. It is particularly useful for culturing cells that are incapable of synthesizing their own biomatrix, including stem cells, and for culturing cells in serum-free medium. Akron’s pFN is a clear, sterile, buffered solution with a pH of about 7.0 to 8.0.