| 产品名称 | CBX1, GST-tag - Proteins - Methyl-lysine Reader(s) |
| 产品货号 | 55009 |
| 产品价格 | 现货询价，电话：010-67529703 |
| 产品规格 | 100 µg |
| 产品品牌 | bpsbioscience |
| 产品概述 | |
| 产品详情 |
Species: Human
Host Species: E. coli
MW: 48.1 kDa
Genbank #: NM_006807
Tag(s): N-terminal GST-tag
a.a: 2–185(end)
Background: Component of heterochromatin. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone
proteins. The protein may play an important role in the epigenetic control of chromatin structure and gene expression. Recognizes and binds histone H3 tails methylated at Lys9, leading to epigenetic repression. Interaction with lamin B receptor (LBR) can contribute to the association of the heterochromatin with the inner nuclear membrane.
Description: Human chromobox homolog 1 (CBX1), also known as p25beta, M31, HP1-beta, and MOD1, GenBank Accession No. NM_006807, a.a. 2-185(end), with N-terminal GST-tag, MW=48.1 kDa, expressed in an E. coli cell expression system.
UniProt P83916
Synonym(s): chromobox homolog 1, CBX1, p25beta, M31, HP1-beta, MOD1
Formulation: 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 16 mM glutathione, and 20% glycerol.
Format: Aqueous buffer solution
Storage / Stability: ≥ 6 months at -80°C Application(s): Useful for protein binding assays, screening inhibitors, and selectivity profiling.
Reference(s): 1. Furuta, K., et al., Chromosoma. 1997 Warning(s): Avoid freeze/thaw cycles
Scientific Category: Methyl-lysine Reader
Product Type: Recombinant Protein
Data shown is lot-specific. Contact us for specific information on other lots.
|
| 产品资料 |
