| 产品名称 | USP33 Core Domain, SUMO-His-tags - Deubiquitylating Enzymes - Ubiquitination |
| 产品货号 | 81102 |
| 产品价格 | 现货询价，电话：010-67529703 |
| 产品规格 | 25 µg |
| 产品品牌 | bpsbioscience |
| 产品概述 | |
| 产品详情 |
Species: Human
Host Species: E. coli
MW: 61 kDa
Genbank #: Q8TEY7
Tag(s): N-terminal SUMO-His-tags
a.a: 181–712
Background: USP33 was originally identified as a protein that interacts with the E3 ubiquitin ligase pVHL, a region commonly mutated in patients with pVHL disease and has been shown to be ubiquitylated by the pVHL E3 ligase complex in vitro and in transiently transfected COS-7 cells. The USP33 catalytic core spans amino acids 181-712.
Description: Human USP33 Core Domain recombinant protein (Genbank Accession No. Q8TEY7), a.a. 181–712, with N-terminal SUMO- and His-tags, expressed in E. coli.
UniProt Q8TEY7
Synonym(s): VHL-interacting deubiquitinating enzyme, Deubiquitinating enzyme 33, KIAA1097, MGC16868, Ubiquitin carboxyl-terminal hydrolase 33, Ubiquitin-specific-processing protease 33, Ubiquitin thioesterase 33, VDU1, USP 33, USP-33
Formulation: 25 mM Tris-HCl, pH 7.5, 150 mM NaCl, 5 mM DTT, 10% glycerol
Format: Aqueous buffer solution
Storage / Stability: Store at or below –80°C. Stable as supplied for up to 1 year when stored dessicated at –80°C. Application(s): This enzyme is active in the Ub-CHOP assay.
Reference(s): 1. De Pitta, C., et al. A leukemia-enriched cDNA microarray platform identifies new transcripts with relevance to the biology of pediatric acute lymphoblastic leukemia. Haematologica 90(7): p. 890-8 (2005).
2. Li, Z., et al., Ubiquitination of a novel deubiquitinati ng enzyme requires direct binding to von Hippel-Lindau tumor suppressor protein. J. Biol. Chem. 277(7): p. 4656-4662 (2002). Warning(s): Avoid freeze/thaw cycles.
Scientific Category: Deubiquitinase
Product Type: Recombinant Protein
Data shown is lot-specific. Contact us for specific information on other lots.
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