| 产品名称 | USP15, SUMO-His-tags |
| 产品货号 | 81100 |
| 产品价格 | 现货询价，电话：010-67529703 |
| 产品规格 | 25 µg |
| 产品品牌 | bpsbioscience |
| 产品概述 | |
| 产品详情 |
Species: Human
Host Species: E. coli
MW: 121 kDa
Tag(s): N-terminal SUMO-His-tags
Background: USP15 is a deubiquitylase that associates with the COP9 signalosome (CSN) complex. It is able to regulate the NF-kappaB pathway by deubquitylating IkappaBalpha2.
Description: Human USP15 recombinant protein, with N-terminal SUMO- and His-tags, expressed in E. coli.
UniProt Q9Y4E8
Synonym(s): Deubiquitinating enzyme 15, KIAA0529, MGC131982, MGC74854, Ubiquitin carboxyl-terminal hydrolase 15, Ubiquitin-specific-processing protease 15, Ubiquitin thioesterase 15, Unph-2, Unph-4, UNPH4, USP 15, USP-15
Assay Conditions: The activity of USP15 and USP2core are measured with 100 nM DiUb48 in 20 mM Tris-HCl, pH 7.5, 150 mM NaCl, 2 mM DTT, 0.02% Tween-20
Formulation: 50 mM Na phosphate pH 7.5, 50 mM NaCl, 1 mM DTT
Format: Aqueous buffer solution
Storage / Stability: Store at or below –80°C. Stable as supplied for up to 1 year when stored dessicated at –80°C. Application(s): This enzyme is active in the Ub-CHOP assay.
Reference(s): 1. Schweitzer K., et al., CSN controls NF-κB by deubiquitinylation of IκBα. EMBO J., 26(6):1532-41 (2007).
2. Hetfeld, BK., et al., The zinc finger of the CSN-associated deubiquitinating enzyme USP15 is essential to rescue the E3 ligase Rbx1. Curr Biol, 15(13):1217-21 (2005). Warning(s): Avoid freeze/thaw cycles.
Scientific Category: Deubiquitinase
Product Type: Recombinant Protein
Data shown is lot-specific. Contact us for specific information on other lots.
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