产品名称 | TAME-HCL |
产品货号 | 27719 |
产品价格 | 现货询价,电话:010-67529703 |
产品规格 | 100 mg |
产品品牌 | bpsbioscience |
产品概述 | |
产品详情 |
MW: 378.9 Da
CAS Registry #: 1784-03-8
Formula: C14H22N4O4S · HCl
Synonym(s): TAME, N2–[(4–Methylphenyl)sulfonyl]–L–arginine methyl ester hydrochloride
Purity: >98% by TLC.
Solubility: Soluble in DMSO (35 mg/ml) or water (35 mg/ml).
Format: White Powder
Application(s): Useful for inhibition of the anaphase-promoting complex (APC)-ubiquitin ligase.
Reference(s): 1. Zeng X. et al. Pharmacologic Inhibition of the Anaphase -Promoting Complex Induces A Spindle Checkpoint-Dependent Mitotic Arrest in the Absence of Spindle Damage. Cancer Cell 2010. 18:382.
2. Zeng X. et al. An APC/C inhibitor stabilizes cyclin B1 by prematurely terminating ubiquitination. Nat. Chem. Biol. 2012. 8:383. Warning(s): Protect from moisture.
Scientific Category: Ubiquitin Enzymes
Product Type: Inhibitors/Activators
Data shown is lot-specific. Contact us for specific information on other lots.
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