产品名称 TAME-HCL
产品货号 27719
产品价格 现货询价,电话:010-67529703
产品规格 100 mg
产品品牌 bpsbioscience
产品概述
产品详情
MW: 378.9 Da
CAS Registry #: 1784-03-8
Formula: C14H22N4O4S · HCl
Synonym(s):
TAME, N2–[(4–Methylphenyl)sulfonyl]–L–arginine methyl ester hydrochloride
Purity:
>98% by TLC.
Solubility:
Soluble in DMSO (35 mg/ml) or water (35 mg/ml).
Format:
White Powder
Application(s):
Useful for inhibition of the anaphase-promoting complex (APC)-ubiquitin ligase.
Reference(s):
1. Zeng X. et al. Pharmacologic Inhibition of the Anaphase -Promoting Complex Induces A Spindle Checkpoint-Dependent Mitotic Arrest in the Absence of Spindle Damage. Cancer Cell 2010. 18:382.
2. Zeng X. et al. An APC/C inhibitor stabilizes cyclin B1 by prematurely terminating ubiquitination. Nat. Chem. Biol. 2012. 8:383.
Warning(s):
Protect from moisture.
Scientific Category:
Ubiquitin Enzymes
Product Type:
Inhibitors/Activators
Data shown is lot-specific. Contact us for specific information on other lots.

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