产品名称 Otub2, His-tag
产品货号 81089
产品价格 现货询价,电话:010-67529703
产品规格 25 µg
产品品牌 bpsbioscience
产品概述
产品详情
Species: Human
Host Species: E. coli
MW: 27 kDa
Genbank #: Q96DC9
Tag(s): His-tag
Background:
Otubain 2 is a member of the OTU (ovarian tumor) superfamily of ubiquitin isopeptidases. It was originally identified as a protein capable of binding ubiquitin aldehyde. Researchers have shown that it is able to cleave tetra-ubiquitin chains in vitro only after removal of a 5 residue C-terminal extension.
Description:
Human Otub2 recombinant protein (Genbank Accession No. Q96DC9), with His-tag, expressed in E. coli.
UniProt
Q96DC9
Synonym(s):
C14orf137, Deubiquitinating enzyme OTUB2, FLJ21916, MGC3102, OTB2, OTU2, Otubain 2, OTU domain-containing ubiquitin aldehyde-binding protein 2, Ubiquitin-specific-processing protease OTUB2, Ubiquitin thioesterase protein OTUB2
Purity:
≥95% by SDS-PAGE
Formulation:
25 mM Tris-HCl, pH 7.5, 150 mM NaCl, 2 mM DTT
Format:
Aqueous buffer solution
Storage / Stability:

Store at or below –80°C. Stable as supplied for up to 1 year when stored dessicated at –80°C.

Application(s):
Human otubain 2 is inactive in vitro against peptide and isopeptide-linked substrates 26, but cleaves Ub-AMC .
Reference(s):
1. Nanao, MH., et al. EMBO Rep. 5, 783-8 (2004).
2. Balakirev, M. et al. EMBO Rep. 2003. 4(5): p517-522.
3. Li, S., et al. J Biol Chem. 285, 4291-7 (2010).
Warning(s):
Avoid freeze/thaw cycles.
Scientific Category:
Deubiquitinase
Product Type:
Recombinant Protein
Data shown is lot-specific. Contact us for specific information on other lots.

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