| 产品名称 | Z-VAD(OMe)-FMK - Inhibitors / Activators - Protease(s) |
| 产品货号 | 27313 |
| 产品价格 | 现货询价，电话：010-67529703 |
| 产品规格 | 5 mg |
| 产品品牌 | bpsbioscience |
| 产品概述 | |
| 产品详情 |
MW: 467.5 Da
CAS Registry #: 187389-52-2
Formula: C22H30FN3O7
Description: Z-VAD(OMe)-FMK is a cell permeable, irreversible pan-caspase inhibitor and anti-apoptotic agent. It has been shown to inhibit Fas-mediated apoptosis in Jurkat T cells and apoptosis in THP.1 cells induced by diverse stimuli (including cycloheximide, thapsigargin, etoposide and staurosporine). Inhibits caspases 1, 3, 4, and 7.
Synonym(s): Benzyloxycarbonyl-Val-Ala-Asp(OMe)-fluoromethylketone, Z-VAD(OMe)-FMK, Z-Val-Ala-Asp(OMe)-FMK, Z-Val-Ala-Asp-FMK, Methyl Ester
Purity: ≥99%
Solubility: DMSO (>10 mg/ml), dimethyl formamide (7 mg/ml) or 100% ethanol (1.3 mg/ml)
Format: A white or off-white solid
Storage / Stability: Store at or below –20°C. Solid form is stable at least 12 months from date of receipt, when stored as directed. Do not store aqueous solutions for more than one day.
Reference(s): Rodríguez-Enfedaque, A., et al. Biochim. Biophys. Acta. 1823: 1343-1352 (2012). Warning(s): Protect from light
Scientific Category: Caspase
Product Type: Inhibitor
Data shown is lot-specific. Contact us for specific information on other lots.
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