| 产品名称 | Renin Assay Kit |
| 产品货号 | 80211 |
| 产品价格 | 现货询价，电话：010-67529703 |
| 产品规格 | 96 reactions |
| 产品品牌 | bpsbioscience |
| 产品概述 | |
| 产品详情 |
Background: Renin is a protease that is synthesized by the kidneys. Renin catalyzes
the hydrolysis of angiotensinogen to angiotensin I, which is converted to angiotensin II, a
highly potent vasoconstrictor. Renin inhibitors have been used therapeutically in the
treatment of hypertension (high blood pressure).
Description: The Renin Assay Kit is designed to
measure Renin activity for screening and profiling applications. It comes in a convenient
96-well format, with purified, activated renin, renin substrate, and assay buffer for 100
enzyme reactions. Aliskiren Hydrochloride is also included as a control for renin
inhibition. The key to the Renin Assay Kit is the specific, fluorogenic substrate. Using this
kit, only one simple step on a microtiter plate is required for renin reactions. The
fluorometric substrate is incubated with a sample containing renin enzyme to produce a
fluorophore that can then be measured using a fluorescence reader.
Synonym(s): Angiotensinogenase
Supplied As: Supplied in a convenient 96-well format, with purified, activated renin, renin substrate, assay buffer, and inhibitor for 100 enzyme reactions.
Contraindications: DMSO >1%, strong acids or bases, ionic detergents, high salt
Format:  Instructions for use: See assay kit data sheet for detailed protocol.
Storage / Stability: At least 12 months from date of receipt, when stored as directed. Kit components require different storage conditions. Be sure to store each component at the proper temperature upon arrival. Reference(s): 1. Paschalidou, K. et al., Biochem. J. 2004; 382: 1031.
2. Gossas, T., et al., Naunyn Schmiedebergs Arch Pharmacol. 2012; 385(2):219-24. Notes: MATERIALS OR INSTRUMENTS REQUIRED BUT NOT SUPPLIED:
Fluorescent microplate reader Warning(s): Avoid freeze/thaw cycles
Scientific Category: Protease
Product Type: Assay Kit
Data shown is lot-specific. Contact us for specific information on other lots.
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| 产品资料 |