产品名称 | Rat Renin, His-tag |
产品货号 | 80201 |
产品价格 | 现货询价,电话:010-67529703 |
产品规格 | 100 µg |
产品品牌 | bpsbioscience |
产品概述 | |
产品详情 |
Species: Rat
Host Species: HEK293 cells
MW: 38.5 kDa
Genbank #: NM_012642
Tag(s): C-terminal His-tag
a.a: 65–402 (end)
Background: Renin is a protease that is synthesized by the kidneys. Renin catalyzes
the hydrolysis of angiotensinogen to angiotensin I, which is converted to angiotensin II, a
highly potent vasoconstrictor. Renin inhibitors have been used therapeutically in the
treatment of hypertension (high blood pressure).
Description: Rat, Activated Renin (GenBank Accession No. NM_012642), a.a. 65 – 402 (end) with C-terminal His-tag, MW=38.5 kDa, expressed in an HEK293 cell expression system.
UniProt P08424
Synonym(s): Angiotensinogenase
Assay Conditions: Assay was performed
using BPS's Renin Assay kit, cat. # 80211, following the recommended assay protocol.
Formulation: 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol.
Format: Aqueous buffer solution
Storage / Stability: >6 months at -80°C. Reference(s): 1. Kedrah, AE., et al., Kidney Blood Press Res. 2012 Jun 6;35(6):425-430.
2. Burnham, CE., et al., Proc Natl Acad Sci USA. 1987 Aug;84(16):5605-5609. Warning(s): Avoid freeze/thaw cycles
Scientific Category: Protease
Product Type: Recombinant Protein
Data shown is lot-specific. Contact us for specific information on other lots.
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产品资料 |