产品名称 Pimobendan
产品货号 27638-2
产品价格 现货询价,电话:010-67529703
产品规格 50 mg
产品品牌 bpsbioscience
产品概述
产品详情
MW: 334.37 Da
CAS Registry #: 74150-27-9
Formula: C19H18N4O2
Target: PDE3
Description:
Pimobendan is a selective inhibitor of PDE3 with IC50 of 0.32 µM.
Synonym(s):
pimobendane; 3-[2-(4-methoxyphenyl)-3H-benzimidazol-5-yl]-4-methyl-4,5-dihydro-1H-pyridazin-6-one
Biological Activity:
Pimobendan exhibits selective inhibition of PDE III isolated from guinea pig cardiac muscle with IC50 of 0.32 uM compared to the inhibition of PDE I and PDE II (IC50s>30 µM). Pimobendan inhibits the activity of cAMP-PDE III with IC50 of 2.4 µM.
Storage / Stability:

Store at or below –20°C. Solid form is stable at least 12 months from date of receipt, when stored as directed. Do not store aqueous solutions for more than one day.

Reference(s):
Boyle KL, Leech E. J Vet Emerg Crit Care (San Antonio). 2012 Aug;22(4):398-408.
Scientific Category:
PDE Inhibitor
Product Type:
Inhibitor
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