Mouse DNA methyltransferase 3β (DNMT3B), GenBank Accession No. NM_001003961, a.a. 2-859 (end), with N-terminal His-tag and C-terminal FLAG-tag, MW = 99 kDa, expressed in Sf9 cells via a Baculovirus expression system.

O88509

DNA

40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 80 ng/µL FLAG peptide, and 20% glycerol.

Aqueous buffer solution

>6 months at –20°C.

Useful for the study of DNA methylation, screening inhibitors, and selectivity profiling.

Application Reference(s):
DNA 5-methylcytosine demethylation activities of the mammalian DNA methyltransferases (2013)

Avoid freeze/thaw cycles.

Methyltransferase

Recombinant Protein