| 产品名称 | Entacapone |
| 产品货号 | 27621-1 |
| 产品价格 | 现货询价，电话：010-67529703 |
| 产品规格 | 10 mg |
| 产品品牌 | bpsbioscience |
| 产品概述 | |
| 产品详情 |
MW: 305.3 Da
CAS Registry #: 130929-57-6
Formula: C14H15N3O5
Target: COMT
Description: Entacapone is a second-generation catechol-O-methyltransferase (COMT) inhibitor
Synonym(s): (E)-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethylprop-2-enamide
Purity: ≥98% by HPLC Biological Activity: Entacapone potently inhibits rat liver total COMT with IC50 and Ki values of 20.1 nM and 10.7 nM respectively. The IC50 values of entacapone against rat liver soluble COMT (S-COMT) and rat liver membrane-bound COMT (MB-COMT) are 14.3 nM and 73.3 nM respectively.
Solubility: Soluble in DMSO 61 mg/ml, water <1 mg/ml, ethanol 2 mg/ml
Storage / Stability: Store at or below –20°C. Solid form is stable at least 12 months from date of receipt, when stored as directed. Do not store aqueous solutions for more than one day. Reference(s): Forsberg M, et al. J Pharmacol Exp Ther. 2003 Feb;304(2):498-506.
Scientific Category: Methyltransferase Inhibitor
Product Type: Inhibitor
Data shown is lot-specific. Contact us for specific information on other lots.
Quality Assurance
|
| 产品资料 |
