Human SetDB1 (variant 2), also known as Histone-lysine Nmethyltransferase SETDB1, SET domain bifurcated 1, KMT1E, ERG-associated protein with SET domain (ESET), GenBank Accession No. NM_012432, a.a. 510- 1290(end) expressed in a Baculovirus Sf9 cell expression system. MW = 114 kDa.

Q15047

Histone-lysine Nmethyltransferase SETDB1, SET domain bifurcated 1, KMT1E, ERG-associated protein with SET domain (ESET)

Assay was performed using the SETDB1 Chemiluminescent Assay Kit, BPS Bioscience Cat. #51056 per the manufacturer’s instructions.

40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 20% Glycerol and 4 mM glutathione

Aqueous buffer solution

>6 months at –80°C.

Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.

1. Dillon, S.C., et al., Genom. Biol. 2005; 6: 227.
2. Schultz, D.C. et al., Genes Dev. 2002; 16: 919-932.

Avoid freeze/thaw cycles. Storing diluted protein is not recommended, if necessary, use carrier protein (BSA 0.1 – 0.5%).

Methyltransferase

Recombinant Protein