| 产品名称 | UBE2O, GST-Tag - Serine-Threonine Kinases - Kinase(s) |
| 产品货号 | 79374 |
| 产品价格 | 现货询价，电话：010-67529703 |
| 产品规格 | 20 µg |
| 产品品牌 | bpsbioscience |
| 产品概述 | |
| 产品详情 |
Species: Human
Host Species: Sf9 insect cells using baculovirus
MW: ~90 kDa
Genbank #: BC022237
Tag(s): N-terminal GST-Tag
Background: UBE2O or ubiquitin-conjugating enzyme E2O is a part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin. HIV-1 Tat has been identified to have a physical interaction with ubiquitin-conjugating enzyme E2O (UBE2O) in human HEK293 and Jurkat cell lines by using affinity tagging and purification mass spectrometry analyses (1).
Description: Recombinant full-length human UBE2O, also known as E2-230K, FLJ12878, and KIAA1734. Genbank Accession BC022237 with an N-terminal GST tag, expressed in Sf9 cells via a baculovirus expression system. MW = 90kDa.
Synonym(s): E2-230K, FLJ12878, KIAA1734
Formulation: 50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Storage / Stability: At least 6 months at –80°C. Avoid freeze/thaw cycles. Application(s): Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Reference(s): 1. Rumbaugh JA. et.al. Neurobiol Dis, 2012 Aug 25. Warning(s): Avoid freeze/thaw cycles
Scientific Category: Ubiquitination
Product Type: Activating Enzyme
Data shown is lot-specific. Contact us for specific information on other lots.
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