产品名称 PKCν (PKCnu), GST-tag - Serine-Threonine Kinases - Kinase(s)
产品货号 40167
产品价格 现货询价,电话:010-67529703
产品规格 10 µg
产品品牌 bpsbioscience
产品概述
产品详情
Species: Human
Host Species: Sf9 insect cells
MW: 142 kDa
Genbank #: NM_005813
Tag(s): N-terminal GST-tag
a.a: full length
Background:
PKCν , also known as PKD3, is a members of the protein kinase C (PKC) family of serine/threonine kinases that play critical roles in the regulation of cellular differentiation and proliferation in many cell types. PKCν is composed of 890 amino acid residues and the protein has 77.3% similarity to human PKCµ (PKCmu) and 77. 4% similarity to mouse PKD (1). The PKCν mRNA is ubiquitously expressed in various tissues and the gene is located between markers WI-9798 and D2S177 on chromosome 2p21 region.
Description:
Recombinant human PKCν (PKCnu), full length, with N-terminal GST-tag, expressed in Sf9 insect cells via a baculovirus expression system.
Synonym(s):
EPK2; PRKCN; PKD3; nPKC-NU; PKCν protein kinase c nu
Purity:
≥75%
Formulation:
50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.25 mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, 25% glycerol.
Format:
Aqueous buffer solution
Storage / Stability:

>6 months at -80°C.

Application(s):
Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Reference(s):
Hayashi,A. et al: PKCnu, a new member of the protein kinase C family, composes a fourth subfamily with PKCmu. Biochim Biophys Acta. 1999 May 6;1450(1):99-106.
Warning(s):
Avoid freeze/thaw cycles
Scientific Category:
Kinase/Serine-Threonine
Product Type:
Recombinant Protein
Data shown is lot-specific. Contact us for specific information on other lots.

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