| 产品名称 | PAK4 - Serine-Threonine Kinases - Kinase(s) |
| 产品货号 | 40076 |
| 产品价格 | 现货询价，电话：010-67529703 |
| 产品规格 | 10 µg |
| 产品品牌 | bpsbioscience |
| 产品概述 | |
| 产品详情 |
Species: Human
Host Species: E. coli
MW: 33.3 kDa
Genbank #: BC002921
Tag(s): none
a.a: 300–591
Background: PAK4 is a recently identified member of the p21-activated kinases (PAKs) which have been implicated in the regulation of cell morphology, motility and transformation. These serine/threonine kinases are activated by and are effectors of small GTPases, cdc 42 and Rac. PAK4 belongs to the Group II PAKs which also includes PAK5 and PAK6. PAK4 has been shown to regulate cell morphology and cytoskeletal organization in mammalian cells.
Description: Human PAK4 (GenBank Accession No. BC002921), a.a. 300-591, MW=33.3 kDa, expressed in E. coli.
Purity: ≥95%
Specific Activity: 5.6 nmoles/min/?g
Formulation: 25 mM Tris-HCl, pH 8, 150 mM NaCl, 10% glycerol, 5 mM DTT
Format: Aqueous buffer solution
Application(s): Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Reference(s): 1. Kimmelman,A.C., et al., Proc. Natl. Acad. Sci. U.S.A. 105 (49), 19372-19377 (2008).
2. Menzel,N., et al., Biochem. J. 416 (2), 231-241 (2008). Warning(s): Avoid freeze/thaw cycles
Scientific Category: Kinase/Serine-Threonine
Product Type: Recombinant Protein
Data shown is lot-specific. Contact us for specific information on other lots.
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