| 产品名称 | p38β, GST-tag - Serine-Threonine Kinases - Kinase(s) |
| 产品货号 | 40143 |
| 产品价格 | 现货询价，电话：010-67529703 |
| 产品规格 | 10 µg |
| 产品品牌 | bpsbioscience |
| 产品概述 | |
| 产品详情 |
Species: Human
Host Species: Sf9 insect cells
MW: 71 kDa
Genbank #: NM_002751
Tag(s): N-terminal GST-tag
a.a: full length
Background: p38β is a member of the p38 MAP kinase family and is activated by both proinflammatory cytokines and environmental stress (1). The p38β is activated through its phosphorylation by MAP kinase kinases (MKKs), preferably by MKK6. Transcription factor ATF2/CREB2 has been shown to be a substrate of this kinase (2). Alternatively spliced transcript variants encoding the same protein have been observed.
Description: Recombinant human p38β (p38beta), full length, with N-terminal GST-tag, expressed in Sf9 insect cells via a baculovirus expression system.
Synonym(s): MAPK11; SAPK2; p38-2; PRKM11; SAPK2B; p38b; P38b2, p38
Purity: ≥75%
Formulation: 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.25 mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, 25% glycerol.
Format: Aqueous buffer solution
Storage / Stability: >6 months at -80°C. Application(s): Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Reference(s): 1. Jiang, Y. et al: Characterization of the structure and function of a new mitogen-activated protein kinase (p38-beta). J. Biol. Chem. 271: 17920-17926, 1996.
2. Stein, B. et al: p38-2, a novel mitogen-activated protein kinase with distinct properties. J. Biol. Chem. 272: 19509-19517, 1997. Warning(s): Avoid freeze/thaw cycles
Scientific Category: Kinase/Serine-Threonine
Product Type: Recombinant Protein
Data shown is lot-specific. Contact us for specific information on other lots.
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