| 产品名称 | MAPKAPK2, His-tag - Serine-Threonine Kinases - Kinase(s) |
| 产品货号 | 40116 |
| 产品价格 | 现货询价，电话：010-67529703 |
| 产品规格 | 10 µg |
| 产品品牌 | bpsbioscience |
| 产品概述 | |
| 产品详情 |
Species: Human
Host Species: Sf9 insect cells
MW: 41 kDa
Genbank #: NM_032960
Tag(s): N-terminal His-tag
a.a: 46–end
Background: MAPKAPK2 (MAPKAP kinase2) is a Ser/Thr protein kinase which is regulated via direct phosphorylation by p38 MAP kinase (1). In conjunction with p38 MAP kinase, MAPKAPK2 is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation and cell proliferation. Heat shock protein HSP27 has been shown to be one of the substrates of MAPKAPK2, in vivo.
Description: Recombinant human MAPKAPK2 (MAPK-activated protein kinase 2), also known as MK2, GenBank Accession #NM_032960, a.a. 46-end, with an N-terminal His-tag, MW = 41 kDa, expressed in Sf9 cells via a baculovirus expression system.
Synonym(s): MK2
Purity: ≥85%
Formulation: 50 mM sodium phosphate, pH 7.5, 300 mM NaCl, 150 mM imidazole, 0.1 mM PMSF, .25 mM DTT, 25% glycerol
Format: Aqueous buffer solution
Storage / Stability: >6 months at -80°C. Application(s): Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Reference(s): 1. Stokoe, D. et al . Biochem. J. 296: 843-849, 1993.
2. Hagood JS, Olman MA. Am. J. Respir. Cell Mol. Biol. 37(5):503-6 (2007). 3. Kotlyarov A, Gaestel M. Biochem. Soc. Trans. 30(Pt 6):959-63 (2002). Warning(s): Avoid freeze/thaw cycles
Scientific Category: Kinase/Serine-Threonine
Product Type: Recombinant Protein
Data shown is lot-specific. Contact us for specific information on other lots.
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