Vascular endothelial growth factor receptor 2 (VEGFR2), also called Kinase insert Domain receptor (KDR), is a tyrosine kinase (TK) receptor for VEGFs that plays a central role in tumor angiogenesis; therefore the inhibition of VEGFR2 is a promising therapeutic strategy for inhibiting angiogenesis and tumor growth. The VEGFR2 Kinase Assay Kit is designed to measure VEGFR2 kinase activity for screening and profiling applications using Kinase-Glo® MAX as a detection reagent.

kdr, Kinase Insert Domain Receptor, VEGFR2, Vascular Endothelial Growth Factor Receptor 2, CD309, FLK-1, Fetal Liver Kinase 1 KDR

The VEGFR2 Kinase Assay Kit comes in a convenient 96-well format, with enough purified recombinant VEGFR2 enzyme, VEGFR2 substrate, ATP and kinase assay buffer for 100 enzyme reactions.

See assay kit data sheet for detailed protocol.

Stable at least 6 months from date of receipt, when stored as directed. Kit components require different storage conditions. Be sure to store each component at the proper temperature upon arrival.

Useful for studying enzyme kinetics and screening small molecular inhibitors for drug discovery and HTS applications.

Sharma, K., et al. Biomed Chromatogr. 2015 Jun; 29(6):803-34.

Fontanella, C., et al. Ann Transl Med. 2014 Dec; 2(12):12

Avoid freeze/thaw cycles.

Kinase

Assay Kit