| 产品名称 | FGR, GST-tag - Kinase Receptor Tyrosine - Kinase(s) |
| 产品货号 | 40422 |
| 产品价格 | 现货询价，电话：010-67529703 |
| 产品规格 | 10 µg |
| 产品品牌 | bpsbioscience |
| 产品概述 | |
| 产品详情 |
Species: Human
Host Species: Sf9 insect cells
MW: 86 kDa
Genbank #: NM_005248
Tag(s): N-terminal GST-tag
a.a: full length
Background: FGR is a protooncogene that is a unique member of the tyrosine kinase gene family. Certain lymphomas (but not sarcomas or carcinomas) express FGR-related messenger RNA. This transcript is detected in Burkitt's lymphoma cell lines naturally infected with Epstein-Barr virus (EBV), but not in EBV-negative Burkitt's lymphoma cells (1). FGR expression is limited to normal peripheral blood granulocytes, monocytes, and alveolar macrophages, all of which contain 50 to 100 copies of c-fgr mRNA per cell (2).
Description: Recombinant full-length human FGR was expressed by baculovirus in Sf9 insect cells using an N-terminal GST-tag. The gene accession number is NM_005248.
Synonym(s): SRC2, c-fgr, p55c-fgr
Purity: ≥95%
Specific Activity: 282 pmol/min/µg
Formulation: 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.25 mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, 25% glycerol.
Format: Aqueous buffer solution
Storage / Stability: >6 months at -80°C Application(s): Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Reference(s): 1. Cheah, MS. et al. Nature. 1986 Jan 16- 22,319(6050):238-40.
2. Willman, CL. et al. Proc Natl Acad Sci U S A. 1987 Jul,84(13):4480-4. Warning(s): Avoid freeze/thaw cycles
Scientific Category: Kinase/Cytoplasmic Tyr
Product Type: Recombinant Protein
Data shown is lot-specific. Contact us for specific information on other lots.
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