产品名称 | VEGFR3(FLT4) Kinase Assay Kit - Kinase(s) |
产品货号 | 79738 |
产品价格 | 现货询价,电话:010-67529703 |
产品规格 | 96 reactions |
产品品牌 | bpsbioscience |
产品概述 | |
产品详情 |
Background: Vascular endothelial growth factor receptor 3 (VEGFR3), also called Fms-Related Tyrosine Kinase 4 (FLT4), is a tyrosine kinase (TK) receptor for VEGFs that plays a central role in tumor angiogenesis; therefore, the inhibition of VEGFR3 is a promising therapeutic strategy for inhibiting angiogenesis and tumor growth.
Description: The VEGFR3 Kinase Assay Kit is designed to measure VEGFR3 kinase activity for screening and profiling applications using ADP-Glo® Kinase Assay as a detection reagent.
Materials Required But Not Provided: ADP-Glo® Kinase Assay (Promega #V6930) Synonym(s): Vascular Endothelial Growth Factor Receptor 3, Fms Related Tyrosine Kinase 4, Tyrosine-Protein Kinase Receptor FLT4, Fms-Like Tyrosine Kinase 4, EC 2.7.10.1
Supplied As: The VEGFR3 Kinase Assay Kit comes in a convenient 96-well format, with enough purified recombinant VEGFR3 enzyme, VEGFR3 substrate, ATP, and kinase assay buffer for 100 enzyme reactions.
Format: Instructions for use: See assay protocol for detailed instructions
Storage / Stability: Up to 6 months when stored as recommended.
Application(s): Useful for studying enzyme kinetics and screening small molecular inhibitors for drug discovery and HTS applications.
Reference(s): Yeh, Yu-Wen et al. “Targeting the VEGF-C/VEGFR3 axis suppresses Slug-mediated
Warning(s): Avoid multiple freeze/thaw cycles.
Scientific Category: Kinase
Product Type: Assay Kit
Data shown is lot-specific. Contact us for specific information on other lots.
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