Human TYK2, also known as PSCTK4, MGC126760, and MGC126762, GenBank Accession No. NM_003331, a.a. 442-1187(end), with N-terminal GST-tag, expressed in a Baculovirus-infected Sf9 cell expression system. MW = 110 kDa.

Tyk2, Tyrosine Kinase 2, JTK1

Aqueous buffer solution.

50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.

At least 6 months at –80°C.

Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.

1. Myers, M.P. et al., JBC. 276: 47771-47774, 2001.
2. Firmbach-Kraft, I. et al., Oncogene. 5(9): 1929-13336. 1990.

Avoid freeze/thaw cycles.

Kinase/Cytoplasmic Tyr

Protein