产品名称 RIPK2 Kinase Assay Kit - Kinase(s)
产品货号 79737
产品价格 现货询价,电话:010-67529703
产品规格 96 reactions
产品品牌 bpsbioscience
产品概述
产品详情
Background:
RIPK2 (receptor-interacting protein kinase 2) has been shown to mediate the activation of pro-inflammatory signals by NODs (Nucleotide-binding oligomerization domain-containing proteins),suggesting RIPK2 may be a promising therapeutic target in autoimmune and inflammatory diseases.
Description:
The RIPK2 Kinase Assay Kit is designed to measure RIPK2 kinase activity for screening and profiling applications using ADP-Glo® Kinase Assay as a detection reagent.
Materials Required But Not Provided:

ADP-Glo® Kinase Assay (Promega #V6930)
Dithiothreitol (DTT, 1 M; optional)
Microplate reader capable of reading luminescence
Adjustable micropipettor and sterile tips
30°C incubator

Synonym(s):
RICK; RIP2; CARD3; CARDIAK; CCK; GIG30
Supplied As:
The RIPK2 Kinase Assay Kit comes in a convenient 96-well format, with enough purified recombinant RIPK2 enzyme, RIPK substrate, ATP and kinase assay buffer for 100 enzyme reactions.
Format:

Assay Kit Components

Instructions for use:
See assay protocol for detailed instructions.
Storage / Stability:
Up to 6 months when stored as recommended.
Application(s):
Useful for studying enzyme kinetics and screening small molecular inhibitors for drug discovery and HTS applications.
Reference(s):

Canning P., et al. Chem. & Biol. 22(9): 1174-1184 (2015)

Warning(s):
Avoid multiple freeze/thaw cycles.
Scientific Category:
Kinase
Product Type:
Assay Kit
Data shown is lot-specific. Contact us for specific information on other lots.

Quality Assurance

Product Datasheets

79737.pdf
产品资料