| 产品名称 | LYNB, GST-tag |
| 产品货号 | 40472 |
| 产品价格 | 现货询价，电话：010-67529703 |
| 产品规格 | 10 µg |
| 产品品牌 | bpsbioscience |
| 产品概述 | |
| 产品详情 |
Species: Human
Host Species: Sf9 insect cells
MW: 85 kDa
Genbank #: BC059394
Tag(s): N-terminal GST-tag
a.a: full length
Background: LYN is a 56 kd tyrosine kinase that is similar to mouse T-lymphocyte-specific tyrosine kinase p56lck, v-yes, v-fgr and v-src and is expressed in a variety of tissues (1). LYN is expressed preferentially in B cells and can be coimmunoprecipitated with IgM suggesting that LYN is physically associated with membrane-bound IgM, and participates in antigen-mediated signal transduction (2). Crosslinking of membrane-bound IgM with antibody induces rapid increase in activities of LYN and LYN-associated phosphatidylinositol 3-kinase.
Description: Recombinant full-length human LYN B was expressed by baculovirus in Sf9 insect cells using an N-terminal GST-tag. The gene accession number is BC059394.
Synonym(s): JTK8, FLJ26625, p65
Specific Activity: 235 pmol/min/µg
Formulation: 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.25 mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, 25% glycerol.
Format: Aqueous buffer solution
Storage / Stability: >6 months at -80°C Application(s): Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Reference(s): 1. Yamanashi, Y. et al. Mol Cell Biol. 1987 Jan;7(1):237-43.
2. Yamanashi, Y. et al. Science. 1991 Jan 11;251(4990):192-4. Warning(s): Avoid freeze/thaw cycles
Scientific Category: Kinase/Cytoplasmic Tyr
Product Type: Recombinant Protein
Data shown is lot-specific. Contact us for specific information on other lots.
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