Human Jak2 (JH2 pseudokinase domain), also known as Janus kinase-2, and Just Another Kinase 2, with W659A, W777A, and F794H mutations. GenBank Accession No. NM_004972, a.a. 536-812, with C-terminal His-Tag, MW=33 kDa, expressed in a Sf9 expression system.

Janus kinase-2, Just Another Kinase 2

≥90%

20 mM Tris pH 8.5, 0.5 mM TCEP and 10% glycerol

Aqueous buffer solution

At least 6 months at –80°C.

1.  Tono, C., et al., Leukemia. 2005; 19(10): 1843-1844.

2.  Goerttler, P.S., et al., Blood. 2005; 106(8): 2862-2864.

Storing diluted enzyme is not recommended, if necessary, use carrier protein (BSA 0.1 – 0.5%). 

Kinase

Protein