产品名称 HCK, GST-tag
产品货号 40440
产品价格 现货询价,电话:010-67529703
产品规格 10 µg
产品品牌 bpsbioscience
产品概述
产品详情
Species: Human
Host Species: Sf9 insect cells
MW: 57 kDa
Genbank #: NM_002110
Tag(s): N-terminal GST-tag
a.a: 230–497
Background:
HCK, a protein-tyrosine kinase belonging to the Src family, is expressed in certain hemopoietic cells and especially prominent in cells of myeloid lineage, particularly mature granulocytes and monocytes (1). HCK gene is located on chromosome sequence 20q11-q12, a region that is affected by interstitial deletions in some acute myeloid leukemias and myeloproliferative disorders suggesting damage to HCK may contribute to the pathogenesis of these conditions (2).
Description:
Recombinant human HCK (230-497) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST-tag. The gene accession number is NM_002110.
Synonym(s):
JTK9
Specific Activity:
171 pmol/min/µg
Formulation:
50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.25 mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, 25% glycerol.
Format:
Aqueous buffer solution
Storage / Stability:

>6 months at -80°C

Application(s):
Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Reference(s):
1. Ziegler, S F. et al. Molec. Cell. Biol. 7: 2276- 2285, 1987.
2. Quintrell, N. et al. Molec. Cell. Biol. 7: 2267- 2275, 1987
Warning(s):
Avoid freeze/thaw cycles
Scientific Category:
Kinase/Cytoplasmic Tyr
Product Type:
Recombinant Protein
Data shown is lot-specific. Contact us for specific information on other lots.

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