c-Mer (MERTK) is a member of the TAM receptor kinases and plays an important role in cell proliferation/survival, adhesion/migration, and regulation of inflammatory cytokine release. Along with other members of this family, Axl and TYRO3, c-Mer is part of an emerging class of innate immune checkpoints participating in antitumoral immunity. Thus, it has been suggested that c-Mer inhibition could be a promising immunotherapeutic approach in cancer treatment. The c-Mer Kinase Assay Kit is designed to measure c-Mer activity for screening and profiling applications using ADPGlo® as a detection reagent.
| 产品名称 | c-Mer Kinase Assay Kit - Kinase(s) |
| 产品货号 | 79660 |
| 产品价格 | 现货询价，电话：010-67529703 |
| 产品规格 | 96 Reactions |
| 产品品牌 | bpsbioscience |
| 产品概述 | |
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Description: Materials Required But Not Provided: ADP-Glo (Promega #V6930),
Dithiothreitol (DTT, 1 M; optional),
Microplate reader capable of reading luminescence,
Adjustable micropipettor and sterile tips,
30°C incubator
Synonym(s): Tyrosine-protein kinase Mer, MERTK, Receptor tyrosine kinase, MerTK
Format: COMPONENTS:
Storage / Stability: Up to 6 months when stored as recommended.
Reference(s): Akalu, Y.T., et. al. Immunological Reviews 276:165-177 (2017)
Warning(s): Avoid multiple freeze/thaw cycles.
Scientific Category: Kinase
Product Type: Assay Kit
Data shown is lot-specific. Contact us for specific information on other lots.
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