| 产品名称 | AXL Kinase Assay Kit - Kinase(s) |
| 产品货号 | 79711 |
| 产品价格 | 现货询价，电话：010-67529703 |
| 产品规格 | 96 reactions |
| 产品品牌 | bpsbioscience |
| 产品概述 | |
| 产品详情 |
Background: AXL (TYRO7) is a receptor tyrosine kinase that is overexpressed in various forms of cancer, including breast, prostate, colorectal, and non-small cell cancers. AXL overexpression has been shown to encourage tumor progression and metastasis and to decrease the anti-tumor immune response, making AXL an attractive candidate for anticancer therapies.
Description: The AXL Kinase Assay Kit is designed to measure AXL kinase activity for screening and profiling applications using ADP-Glo® Kinase Assay as a detection reagent.
Materials Required But Not Provided: ADP-Glo® Kinase Assay (Promega #V6930) Synonym(s): AZF, AZFA, SP3, AZF1, ARK, JTK11, Tyro7, UFO, AXL receptor tyrosine kinase
Supplied As: The AXL Kinase Assay Kit comes in a convenient 96-well format, with enough purified recombinant AXL enzyme, AXL substrate, ATP and kinase assay buffer for 100 enzyme reactions.
Format:
Instructions for use: See assay protocol for detailed instructions.
Storage / Stability: Up to 6 months when stored as recommended.
Application(s): Useful for studying enzyme kinetics and screening small molecular inhibitors for drug discovery and HTS applications.
Reference(s): 1. Wu, X., Liu, X., Koul, S., Lee, C.Y., Zhang, Z., Halmos, B. AXL kinase as a novel target for cancer therapy. Oncotarget. 2014; 5(20):9546-63. 2. Rankin, E.B., Giaccia, A.J. The Receptor Tyrosine Kinase AXL in Cancer Progression. Cancers (Basel). 2016; 8(11):103. Warning(s): Avoid multiple freeze/thaw cycles.
Scientific Category: Kinase
Product Type: Assay Kit
Data shown is lot-specific. Contact us for specific information on other lots.
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