A novel geldanamycin fluorescent probe optimized for use with BPS's HSP90 Assay Kits. May also be used for detection of cell surface HSP90.

≥98%

FITC-labeled geldanamycin has been shown to inhibit HSP90 protein with an IC50 of 60 nM and HSP90 with an IC50 of 84 nM as shown. Measured using the HSP90 Assay Kits.

2.5 µM

C55H63N5O13S

DMSO solution (2.5 µM)

>6 months at -80°C

Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.

1. Kim, J., et al., Biomol. Screening 2004; 9(5): 375-381.
2. Howes, R., et al., Anal. Biochem. 2006; 350:202-213.

Avoid freeze/thaw cycles. Keep DMSO stock solutions out of contact with air. Protect from light.

Heat Shock Proteins

Assay Kit Component