产品名称 Parthenolide
产品货号 27768-2
产品价格 现货询价,电话:010-67529703
产品规格 50 mg
产品品牌 bpsbioscience
产品概述
产品详情
MW: 248.3 Da
CAS Registry #: 20554-84-1
Formula: C15H20O3
Target: HDAC1
Background:
Parthenolide is a sesquiterpene lactone and the active principle of feverfew (Chrysanthemum parthenium)
Description:
Parthenolide specifically inhibits HDAC1 without affecting other class I/II HDACs.
Synonym(s):
(1aR,7aS,10aS,10bS,E)-1a,5-dimethyl-8-methylene-2,3,6,7,7a,8,10a,10b-octahydrooxireno[2',3':9,10]cyclodeca[1,2-b]furan-9(1aH)-one
Solubility:
Soluble in DMSO (100 mg/ml) or 100% ethanol (20 mg/ml).
Format:
white to off-white crystalline solid.
Storage / Stability:

Store at or below –20°C. Solid form is stable at least 12 months from date of receipt, when stored as directed. Do not store aqueous solutions for more than one day.

Reference(s):
1. Gopal, Y.N.V., et al. 2007. Chemistry and Biology 14(7) 813-823.
2. Groenewegen, W.A., et al. 1990. J. Pharm. Pharmacol. 42: 553-557.
3. 2. Sumner, H., et al. 1992. Biochem. Pharmacol. 43: 2313-2320.
4. 3. Barsby, R.W., et al. 1992. J. Pharm. Pharmacol. 44 :737-740.
Scientific Category:
Deacetylase Inhibitor
Product Type:
Inhibitor
Data shown is lot-specific. Contact us for specific information on other lots.

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