Human secreted TIM-3, Fc fusion protein, also known as T-cell immunoglobulin mucin receptor 3, T-cell membrane protein 3, T-cell and immunoglobulin and mucin domain-containing protein 3, TIMD-3, Hepatitis A virus cellular receptor 2, and HAVCR-2. GenBank Accession No. NM_032782.4, a.a. 22-200 expressed in a HEK293 cell expression system. MW = 46.5 kDa. This protein runs at a higher MW by SDS-PAGE due to glycosylation.

Q8TDQ0

T-cell immunoglobulin mucin receptor 3, T-cell membrane protein 3, T-cell and immunoglobulin and mucin domain-containing protein 3, TIMD-3, Hepatitis A virus cellular receptor 2, HAVCR-2, Tim

<1 EU/µg

40 mM Tris, pH 8.0, 110 mM NaCl, 2.4 mM KCl, and 20% glycerol.

Aqueous buffer solution

At least 6 months at –80°C.

1. Zhu, C. et al., Nat. Immunol. 2005; 6:1245-1252.
2. Anderson, A.C. et al., Science. 2007; 318(5853):1141-1143.

The aggregation state of this product has been confirmed to be <10%.

Avoid freeze/thaw cycles. Protein may be diluted to ≥ 100 μg/ml in PBS + glycerol and stored at -80°C.

Immunotherapy

Recombinant Protein